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HATICE

Healthy AgingThrough Internet Counsellingin the Elderly

Collaborative project co-funded by the European Unions' Seventh Framework Programme (FP7, 2007-2013) under grant agreement No 305374.

Flag of the European Union FP7 Cooperation logo

HATICE is the first major research project following the launch of the European Dementia Prevention Initiative (EDPI) in 2011. Cardiovascular risk factors including hypertension, diabetes, obesity, smoking and lack of physical exercise are common in the elderly and increase the risk of myocardial infarction, stroke and dementia.

Main aims of HATICE:
  1. Develop an innovative, interactive internet intervention platform to optimise treatment of cardiovascular disease in the elderly
  2. Test this new intervention in a randomised controlled trial to investigate whether new cardiovascular disease and cognitive decline can be prevented

HATICE results published in Lancet Digital Health

The HATICE trial has shown that older people can improve their lifestyle and adopt healthier behaviours with the support of an online coach. This way they can reduce their risk of cardiovascular disease and dementia. These results were published in The Lancet Digital Health on 14 November 2019.

After 18 months in the coach supported internet intervention, 90% of the treatment group set one or more goals related to their lifestyle, with the support of their coach. The researchers investigated the effect on a composite measure for cardiovascular disease risk, including blood pressure, body mass index (BMI) and cholesterol. The research shows that the treatment group had a modest, but significant improvement compared to the control group. This effect was largest in those participants who were most active on the website: for each additional goal set, the score representing the risk of cardiovascular disease improved.

These results are promising, but the researchers stress that prevention requires a long-term effort. Lead investigator Dr. Edo Richard: ‘Although the magnitude of the effect is relatively small, with this type of approach it takes time and larger effects are more likely in people with a higher risk of cardiovascular disease or those with less access to health care, such as people in low- and middle-income countries, but also people with low social advantage in Europe’.

The research also shows, according to co-lead investigator Dr. Eric Moll van Charante, that modern technology in the form of self-management with an online coach can be a valuable addition to regular health care, also in older persons. ’The results invite testing this type of intervention on a larger scale to confirm whether the beneficial effects we see are sustainable over time and eventually lead to fewer heart attacks, strokes and dementia in the long term’.

https://www.thelancet.com/journals/landig/article/PIIS2589-7500(19)30194-3/fulltext

Second HATICE PhD thesis defense by Cathrien Beishuizen

On April 12th 2018, Cathrien Beishuizen defended the second PhD thesis based on HATICE. Cathrien was involved in the development of the HATICE-platform, including the performance of a systematic review and meta-analysis on the effectiveness of internet-interventions for cardiovascular risk self-management and qualitative research with primary care nurses. Further she qualitatively investigated engagement of HATICE participants with the HATICE-platform and studied determinents of dropout and non-adherence in the PreDIVA trial. This thesis provides starting points on how to develop an eHealth application for cardiovascular self-management for older people. The results of this thesis indicate that human support forms an essential component of internet-interventions to increase their effectiveness and stimulate engagement. For more information, or a copy of the thesis, please contact Cathrien: c.r.beishuizen[at]amc.uva.nl

In March 2018, Cathrien started her training to become a general practitioner at the AMC, the Netherlands.